1. Melamine is being described as "harmful if swallowed,
inhaled or absorbed through the skin. Chronic exposure may cause
cancer or reproductive damage. Eye, skin and respiratory
2. Generally, consumption of melamine alone is of low toxicity.
3. However, when it combines with cyanuric acid (a by-product of
melamine during melamine preparation, it may be added into food)
to form melamine cyanurate, this compound has high toxicity and
may cause acute kidney stone.
4. When we chronically ingest small quantity of melamine and
cyanuric acid from foods, they will be absorbed into our
bloodstream, reacting with each other to form melamine cyanurate
and concentrate in the urine-filled renal microtubules.
5. As time passes, the amount of melamine cyanurate that is
concentrated in kidneys will increase.
Melamine cyanurate has very low solubility – they start to
crystallize and form large numbers of round yellow crystals in
6. These melamine crystals will then block and damage the renal
cells that line in tube, causing the kidneys to malfunction or
7. Besides, ingestion of melamine may also damage our
reproductive system and causes cancer.
8. According to the information provided by World Health
Organization, the Tolerable Daily Intake (TDI) for melamine (the
amount of melamine a person could stand per day without
incurring a bigger health risk) is 0.2 mg per kg of body mass.