Why It's Hard To Lose Weigh
ONE of the
most frustrating mysteries of weight loss is why the weight seem
to inevitably pile back on, following a successful diet.
Researchers found that being obese can reset "normal" body
weight to a permanently elevated level.
mice found that the longer the animals remained overweight, the
more likely their condition would become "irreversible", making
it difficult to maintain meaningful weight loss.
demonstrates that obesity is in part a self-perpetuating
disorder and the results further emphasize the importance of
early intervention in childhood to try to prevent the condition
whose effects can last a lifetime.
remained at a healthy weight into young adulthood by strict
dieting alone were able to maintain normal weight without
dieting after turning on the switch.
chronically overfed mice with the earliest onset of obesity
never completely returned to normal weight after flipping the
switch, despite marked reduction in food intake and increased